New substituted pentabasic azaheterocyclic compounds and its...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 277/22 (2006.01) A61K 31/426 (2006.01)

Patent

CA 2640396

The substituted pentabasic azaheterocyclic compounds of formula I and/or its pharmacological salts and hydrates are provided in the present invention, the groups in the formula are defined as the description. The medicinal composition comprising above-mentioned compounds and/or its pharmacological salts and hydrates is also provided, and the application of the said medicinal composition in preparing medicines for preventing or treating the diseases related with AGEs, and in preparing oral preparation for inhibiting or reversing discoloration of teeth, and in preparing antistaling agent of animals and plants protein are disclosed.

L'invention concerne des composés azahétérocycliques pentabasiques de la formule 1 et/ou leurs sels et hydrates pharmacologiques, les groupes de la formule étant tels que définis dans la description. L'invention porte aussi sur une composition médicinale renfermant les composés précités et/ou leurs sels et hydrates pharmacologiques, et sur l'utilisation de ladite composition médicinale dans la préparation de médicaments destinés à prévenir ou à traiter des maladies liées au vieillissement, dans la préparation d'une formulation orale destinée à inhiber ou à inverser la décoloration des dents, et dans la préparation d'un agent retardant le rassissement de protéines animales et végétales.

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