New therapeutic applications of n-cyclohexylbenzamides

A - Human Necessities – 61 – K

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A61K 31/445 (2006.01) A61K 31/435 (2006.01)

Patent

CA 2221863

The use of compounds of formula (I), wherein R1 is a straight, branched or cyclised C1-5 alkyl radical, and R2 is a hydrogen atom, a straight or branched C1-5 alkyl radical, a hydroxyl radical, a C1-5 alkoxy radical or a C1-2 hydroxyalkyl radical, and R3 is a hydrogen atom, or R2 and R3 are both a C1-5 alkyl radical, said compounds having a 2R configuration; racemic forms comprising said compounds; and pharmaceutically acceptable salts thereof; for making a drug for the treatment of visceral pain, is disclosed.

La présente invention concerne l'utilisation des composés de formule (I), dans laquelle R1 est un radical alkyle linéaire, ramifié ou cyclisé en C1-C5 et R2 représente un atome d'hydrogène, un radical alkyle linéaire ou ramifié en C1-C5, un radical hydroxyle, un radical alkoxy en C1-C5 ou un radical hydroxyalkyle en C1-C2, et R3 représente un atome d'hydrogène ou R2 et R3 représentent tous les deux un radical alkyle en C1-C5, ces composés étant de configuration 2R, ainsi que des racémiques comprenant ces composés, et de leurs sels pharmaceutiquement acceptables, pour la fabrication d'un médicament destiné au traitement des douleurs d'origine viscérale.

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