New therapeutic approaches for treating alzheimer disease...

A - Human Necessities – 61 – K

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A61K 45/06 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2722453

The present invention relates to compositions and methods for the treatment of Alzheimer's disease and related disorders. More particularly, the invention relates to combined therapies that modulate angiogenesis for treating said disease. In a preferred embodiment, the invention relates to a composition comprising a combination of at least two compounds chosen from the group consisting a leflunomide, sulf isoxazole, terbinafine, baclofen, clopidogrel, fenoldopam, mepacrine and phenformin, or salts or prodrugs or derivatives or sustained release formulations thereof, for simultaneous, separate or sequential administration.

La présente invention concerne des compositions et des méthodes de traitement de la maladie d'Alzheimer et des troubles qui lui sont associés. Elle concerne plus particulièrement des thérapies qui modulent l'angiogenèse pour le traitement de cette maladie.

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