New therapeutic use for a group of sulphated polysaccharides

A - Human Necessities – 61 – K

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A61K 31/737 (2006.01) A61P 19/02 (2006.01)

Patent

CA 2555616

The present invention relates to the use of a sulphated polysaccharide in acid form or as a physiologically acceptable salt thereof, selected from the group consisting of inulin sulphate, gellan sulphate, pullulan sulphate, curdlan sulphate, alginiq acid sulphate, laminarin sulphate, and pectin sulphate, for the preparation of a medicament for the treatment or prophylaxis of arthrosis in a mammal. Preferably, the sulphated polysaccharide is inulin sulphate, most preferably inulin polysulphate sodium salt. The present invention also relates to the use of a sulphated oligosaccharide derived from a polysaccharide selected from the group consisting of inulin, gellan, pullulan, curdlan, alginic acid, laminarin, and pectin, for the preparation of a medicament for the treatment or prophylaxis of arthrosis in a mammal.

La présente invention se rapporte à l'utilisation d'un polysaccharide sulfaté sous forme acide, ou de son sel physiologiquement acceptable, choisi dans le groupe constitué du sulfate d'inuline, du sulfate de gellane, du sulfate de pullulane, du sulfate de curdlane, du sulfate d'acide alginique, du sulfate de laminarine et du sulfate de pectine, dans la préparation d'un médicament destiné au traitement ou à la prévention de l'arthrose chez un mammifère. Le polysaccharide sulfaté est de préférence le sulfate d'inuline, et plus préférentiellement encore un sel de sodium de polysulfate d'inuline. La présente invention se rapporte également à l'utilisation d'un oligosaccharide sulfaté dérivé d'un polysaccharide choisi dans le groupe constitué d'inuline, gellane, pullulane, curdlane, acide alginique, laminarine et pectine, dans la préparation d'un médicament destiné au traitement ou à la prévention de l'arthrose chez un mammifère.

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