New topical compositions in the form of o/w liquid emulsion...

A - Human Necessities – 61 – K

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A61K 9/107 (2006.01) A61K 8/06 (2006.01) A61K 8/34 (2006.01) A61K 8/81 (2006.01) A61K 47/10 (2006.01) A61K 47/34 (2006.01) A61Q 19/00 (2006.01)

Patent

CA 2214909

This invention concerns a new composition in the form of an oil-in-water liquid emulsion (O/W) for topical application, consisting of between 30% and 50% by weight in relation to the total weight of the composition of at least one glycol, an appropriate emulsifying system and at least one active agent. The liquid composition, according to the invention, has a viscosity, preferably, of between 3 and 10 Pas (3,000 and 10,000 cP), viscosity measured with a Brookfield viscometer, model LVDV II + mobile No. 4, at a speed of 30 rpm for 30 seconds and a temperature of 25°C +/- 3°C. The high glycol content promotes the penetration of the active agent into the skin.

La présente invention concerne une nouvelle composition sous forme d'émulsion fluide de type huile dans eau (H/E) pour une application topique, comprenant entre 30 à 50% en poids par rapport au poids total de la composition d'au moins un glycol, un système émulsionnant approprié et au moins un agent actif. La composition fluide selon l'invention a de préférence une viscosité comprise entre 3 et 10 Pa.s (3000 et 10000 centipoises), viscosité mesurée avec un appareil Brookfield modèle LVDV II + mobile n° 4, à une vitesse de 30 tours/mn pendant 30 secondes et à une température de 25°C +/- 3°C. La forte teneur en glycol favorise la pénétration de l'agent actif dans la peau.

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