C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/30 (2006.01) A61K 39/012 (2006.01) C07K 14/45 (2006.01) C07K 16/20 (2006.01) C12N 5/10 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2159958
The present invention relates to peptides immunoreactive with antibodies to Toxoplasma gondii, nucleic acid sequences encoding these peptides, recombinant vector molecules, comprising these nucleic acid sequences, host cells transformed with the recombinant vector molecule, immunochemical reagents comprising the peptidesor antibodies directed against the peptides, a test kit for the detection of T. gondii infections as well as a vaccine for the protection against T. gondii infections.In particular the present invention provides peptides comprising part of the amino acid sequence as shown in SEQ ID No.: 1. A preferred embodiment of the present invention are peptides comprising at least part of the amino acid sequence shown in SEQ ID No.: 3 or 5. It has been found that the peptides according to the present invention are particularly suitable for diagnosing T. gondii infected humans.
de Haard Johannes Jozef Wilhelmus
Koolen Marcus Josephus Marie
Akzo Nobel Nv
Fetherstonhaugh & Co.
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