New triazolopurines, method of preparing them and their use...

Details New triazolopurines, method of preparing them and their use... New triazolopurines, method of preparing them and their use...

C - Chemistry, Metallurgy

07

D

C07D 473/18 (2006.01) A61K 31/52 (2006.01) A61K 31/53 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07D 487/14 (2006.01)

Patent

CA 2256736

The invention pertains to triazolopurines of formula (I). The claimed compounds show an affinity to adenosine receptors and thus represent a new class of adenosine antagonists. Generally, adenosine antagonists can have a therapeutically useful effect in cases where diseases or pathological situations involve activation of adenosine receptors.

L'invention concerne des triazolopurines de formule (I). Les composés de l'invention présentent une affinité vis-à-vis des récepteurs d'adénosine et constituent ainsi une nouvelle catégorie d'antagonistes de l'adénosine. En général, les antagonistes d'adénosine peuvent avoir un effet utile sur le plan thérapeutique dans les cas où les maladies ou les états pathologiques sont liés à une activation des récepteurs d'adénosine.

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