New use

Details New use New use

A - Human Necessities

61

K

A61K 31/70 (2006.01) A61K 31/7032 (2006.01) A61P 17/06 (2006.01) A61P 43/00 (2006.01) C07H 15/04 (2006.01) C07H 15/06 (2006.01) C07H 15/10 (2006.01)

Patent

CA 2253440

The invention refers to the use of a sulpholipid SQDG having formula (I), wherein R1 and R2, which are the same or different, are hydrogen or saturated or unsaturated, optionally hydroxy-substituted acyl groups, protonated or as a salt, for the preparation of a pharmaceutical composition for the treatment of inflammatory skin diseases or disorders, especially psoriasis. A pharmaceutical composition comprising an SQDG compound in combination with a polyunsaturated fatty acid and a therapeutically acceptable carrier is also described.

L'invention concerne l'utilisation d'un sulfolipide du type sulfoquinovosyldiacylglycérol ayant la formule (I). Dans cette formule, R¿1? et R¿2?, qui sont identiques ou différents, sont l'hydrogène ou des groupes acyle saturés ou insaturés, éventuellement hydroxy substitués. Le composé de l'invention peut être utilisé sous la forme protonique ou comme sel, pour la préparation d'une composition pharmaceutique, utilisable pour le traitement des dermatoses inflammatoires, en particulier du psoriasis. On décrit, également, une composition pharmaceutique contenant le composé selon l'invention, combiné à un acide gras polyinsaturé et un vecteur, acceptable sur le plan pharmaceutique.

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