New use 938

Details New use 938 New use 938

A - Human Necessities

61

K

A61K 31/522 (2006.01) A61K 31/519 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2698205

The present invention relates to the use of 2-thioxo-1,2, 3, 5- tetrahydro- pyrrolo[3,2-d]pyrimidine-4-one, thioxanthine and 2- thioxo -1,2,3,7 -tetrahydro-6H-purin-6-one derivatives as MPO inhibitors for the treatment of multiple system atrophy (MSA), Huntington' s disease (HD).

L'invention concerne l'utilisation de dérivés de thioxo-1,2,3,5-tétrahydro-pyrrolo[3,2-d]pyrimidine-4-one, de thioxanthine et de 2-thioxo-1,2,3,7-tétrahydro-6H-purin-6-one en tant qu'inhibiteurs de MPO pour le traitement de l'atrophie multi-systématisée (AMS), la maladie de Huntington (HD).

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