C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 451/04 (2006.01) A61K 31/40 (2006.01) A61K 31/439 (2006.01) A61K 31/444 (2006.01) A61K 31/46 (2006.01) A61P 25/00 (2006.01) C07D 453/02 (2006.01) C07D 453/06 (2006.01) C07D 487/08 (2006.01)
Patent
CA 2389604
This invention relates to new use of a compound of general formula (I) wherein: A represents (II), (III), (IV), (V), (VI); D represents oxygen, or sulfur; R1 represents hydrogen or methyl; R2 represents hydrogen, or C1-C4 alkyl; and R3 represents (A), (B), (C), or an enantiomer thereof, and pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, especially in the treatment of prophylaxis of psychotic disorders and intellectual impairment disorders.
Cette invention concerne la nouvelle utilisation d'un composé de la formule générale (I) où: A représente (II), (III), (IV), (V) et (VI); D représente de l'oxygène ou du soufre; R?1¿ représente de l'hydrogène ou du méthyle; R?2¿ représente de l'hydrogène ou alkyle en C¿1?-C¿4?; et R?3¿ représente (VII), (VIII), (IX) ou un de leurs énantiomères, et leurs sels pharmaceutiquement compatibles, leurs procédés de production, les compositions pharmaceutiques les contenant et leur utilisation en thérapie, notamment dans le traitement ou la prévention de troubles psycotiques et d'un déficit intellectuel.
Balestra Michael
Mullen George
Phillips Eifion
Schmiesing Richard
Astrazeneca Ab
Fetherstonhaugh & Co.
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