New use of citreamicins

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/42 (2006.01) A61K 31/122 (2006.01) A61K 31/352 (2006.01) A61K 35/74 (2006.01)

Patent

CA 2408837

Citreamicins possess useful antitumor activity. Typically they are of formula (I), wherein R1 is selected from the group consisting of COCH2CH(CH3)2, COCH(CH3)2, COCH3 or H when R2 is CH3, or wherein R1 is COCH2CH(CH3)2 and R2 is H.

L'invention concerne des citre-amicines possédant une activité antitumorale utile. Ces citre-amicines sont représentées par la formule (I), dans laquelle R¿1? représente un groupe COCH¿2?CH(CH¿3?)¿2?, COCH(CH¿3?)¿2?, COCH¿3? ou un atome H lorsque R¿2? représente un groupe CH¿3?, ou dans laquelle R¿1? représente un groupe COCH¿2?CH(CH¿3?)¿2? et R¿2? représente un atome H.

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