A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/04 (2006.01) A61K 31/00 (2006.01) A61K 31/196 (2006.01) A61K 31/21 (2006.01) A61K 31/216 (2006.01) A61K 31/33 (2006.01) A61K 31/381 (2006.01) A61K 31/403 (2006.01) A61K 31/4035 (2006.01) A61K 31/405 (2006.01) A61K 31/407 (2006.01) A61K 45/06 (2006.01) A61P 1/04 (2006.01) A61P 31/00 (2006.01)
Patent
CA 2373653
The present invention discloses a new use of NO-releasing NSAIDs, especially NO-releasing NSAIDs of formula (I), or a pharmaceutically acceptable salt or enantiomer thereof, for the manufacture of a medicament for the treatment of bacterial infections, especially caused or mediated by Helicobacter pylori. Disclosed is also the new use of a NO-releasing NSAID in combination with an acid susceptible proton pump inhibitor for the treatment of bacterial infections.
La présente invention concerne une nouvelle utilisation d'AINS à libération de NO, particulièrement les AINS à libération de NO représentés par la formule (I), ou un sel de ceux-ci acceptable sur le plan pharmaceutique ou un énantiomère, destinée à la fabrication d'un médicament devant traiter les infections bactériennes, particulièrement celles provoquées ou véhiculées par <i>Helicobacter pylori</i>. En outre, cette invention concerne la nouvelle utilisation d'AINS à libération de NO en association avec un inhibiteur de pompe à protons sensible à l'acide pour traiter les infections bactériennes.
Eek Arne
Raud Johan
Astrazeneca Ab
Fetherstonhaugh & Co.
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