New use, pharmaceutical preparations as well as a process...

Details New use, pharmaceutical preparations as well as a process... New use, pharmaceutical preparations as well as a process...

A - Human Necessities

61

K

A61K 9/08 (2006.01) A61K 9/19 (2006.01) A61K 31/185 (2006.01) A61K 31/675 (2006.01) A61K 47/20 (2006.01) A61K 47/26 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2540537

The invention concerns the use of mercaptoethane sulfonate-sodium (Mesna) to increase the solubility of the Ifosfamide in storage-stable, concentrated and/or highly-concentrated (supersaturated) aqueous pharmaceutical Ifosfamide preparations for parenteral administration as well as a process for their production.

L'invention concerne l'utilisation d'un mercaptoéthane sulfonate de sodium (Mesna) pour augmenter la solubilité de l'ifosfamide dans des préparations pharmaceutiques d'ifosfamide aqueuses concentrées et/ou hautement concentrées (sursaturées) stables au stockage destinées à une administration parentérale, ainsi qu'un procédé pour leur production.

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