New uses for 4,17.beta.-dihydroxyandrost-4-ene-3-one

A - Human Necessities – 61 – K

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Details

A61K 31/568 (2006.01) A61K 45/06 (2006.01) A61P 5/26 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2651354

The present invention relates to novel uses of 4,17.beta. dihydroxyandrost-4-ene-3-one (hereinafter 4-hydroxytestosterone), to a process for their preparation, to pharmaceutical compositions containing them, and to the use of said compounds for the prophylaxis and/or treatment of breast cancer in mammals irrespective of the estrogen- receptor status of the tumor.

L'invention concerne de nouveaux procédés d'utilisation de 4,17ß-dihydroxyandrost-4-ène-3-one (appelée ci-après 4-hydroxytestostérone), un procédé destiné à préparer ces composés, des compositions pharmaceutiques les contenant, et leur utilisation pour la prophylaxie et/ou le traitement du cancer du sein chez les mammifères, indépendamment de l'état du récepteur d'oestrogène de la tumeur.

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