New vaccine formulations - 1

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/00 (2006.01) A61K 35/56 (2006.01) A61P 35/00 (2006.01) C12N 5/00 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2373730

The invention relates to new vaccines for use as immunotherapeutic agents in the treatment of cancer particularly but not limited to prostate cancer. Further the invention relates to alternative culture techniques which offer improved scale-up and processing benefits and significantly improve the activity of vaccines based on whole allogeneic cells or derivatives thereof. It further relates to a method of producing whole cell cancer vaccines which comprise culturing malignant cells under conditions which are not conventional static 2D culture techniques.

L'invention concerne de nouveaux vaccins utilisés comme agents immunothérapiques dans le traitement de cancer plus particulièrement celui de la prostate, mais pas uniquement. En outre, l'invention concerne diverses techniques de culture offrant des mises à l'échelle améliorées et des avantages de traitement, et améliorant de manière significative l'activité des vaccins à base de cellules allogéniques entières ou de leurs dérivés. L'invention concerne également une méthode de production de vaccins contre le cancer, à base de cellules entières, ainsi que la culture de cellules malignes dans des conditions de techniques de culture 2D statiques non conventionnelles.

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