C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 205/08 (2006.01) A61K 31/397 (2006.01) A61P 3/06 (2006.01) A61P 9/10 (2006.01) A61P 25/28 (2006.01)
Patent
CA 2609994
The invention relates to novel 2-azetidinone derivatives of formula (I) and to pharmaceutically acceptable salts, solvates and prodrugs thereof . The compounds are cholesterol absorption inhibitors, useful in the treatment of hyperlipidaemic conditions. The invention also relates to processes for their manufacture and to pharmaceutical compositions containing them.
La présente invention a pour objet de nouveaux dérivés de la 2-azétidinone de formule (I) et des sels, solvates ou promédicaments pharmaceutiquement acceptables de ceux-ci. Les composés sont des inhibiteurs de l'absorption du cholestérol, utiles pour le traitement de conditions d~hyperlipidémie. L'invention concerne aussi des méthodes pour leur préparation et des compositions pharmaceutiques qui les contiennent.
Dahlstroem Mikael
Hunegnaw Fana
Karlsson Staffan
Nordberg Peter
Starke Ingemar
Astrazeneca Ab
Fetherstonhaugh & Co.
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