Ngzipa, ngzipd, pgzipa, and pgzipd polynucleotides and...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) A61P 3/00 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2462588

The present invention relates to the field of metabolic research. Metabolic disorders, such as obesity, are a public health problem that is serious and widespread. NGZIPA, NGZIPD, PGZIPA or PGZIPD polypeptides have been identified that are believed to be beneficial in the treatment of metabolic disorders. These compounds should be effective for reducing body mass and for treating metabolic-related diseases and disorders. These metabolic-related diseases and disorders include hyperlipidemias, atherosclerosis, diabetes, and hypertension.

L'invention concerne le domaine de la recherche métabolique. Les troubles métaboliques tels que l'obésité, sont un problème de santé publique sérieux et étendu. L'invention concerne également des polypeptides NGZIPA, NGZIPD, PGZIPA ou PGZIPD identifiés présentant des effets bénéfiques dans le traitement des troubles métaboliques. Ces composés sont efficaces pour réduire la masse corporelle et pour traiter des maladies et des troubles liés au métabolisme. On peut citer à titre d'exemple de ces maladies et de ces troubles liés au métabolisme: l'hyperlipidémie, l'athérosclérose, le diabète et l'hypertension.

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