C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 409/10 (2006.01) A61K 31/381 (2006.01) A61K 31/395 (2006.01) A61K 31/415 (2006.01) A61K 31/426 (2006.01) A61K 31/4709 (2006.01) A61P 3/00 (2006.01) A61P 9/10 (2006.01) C07D 231/14 (2006.01) C07D 277/56 (2006.01) C07D 333/38 (2006.01) C07D 417/10 (2006.01)
Patent
CA 2622960
A method of treating atherosclerosis and related conditions using compounds of formula I: as well as pharmaceutically acceptable salts and solvates is disclosed. The compounds are useful for treating dyslipidemias, and in particular, reducing serum LDL, VLDL and triglycerides, and raising HDL levels.
L'invention concerne une méthode de traitement de l'athérosclérose et d'états pathologiques apparentés, qui utilise des composés représentés par la formule I ainsi que des sels et solvates pharmaceutiquement acceptables de ceux-ci. Ces composés sont utiles pour traiter des dyslipidémies, et en particulier pour réduire les taux sériques de LDL, de VLDL et de triglycérides, et augmenter les taux de HDL.
Beresis Richard Thomas
Colletti Steven L.
Frie Jessica Leslie
Imbriglio Jason E.
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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