Niacin receptor agonists, compositions containing such...

A - Human Necessities – 61 – K

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A61K 31/551 (2006.01)

Patent

CA 2620570

Compounds of the formula (I): as well as pharmaceutically acceptable salts and solvates are disclosed. The compounds are useful for treating dyslipidemias, and in particular, reducing serum LDL, VLDL and triglycerides, and raising HDL levels. Pharmaceutical compositions and methods of treatment are also included.

L'invention concerne des composés représentés par la formule générale (I), ainsi que des sels et des solvates de qualité pharmaceutique. Ces composés sont utiles pour le traitement de dyslipidémies et, plus précisément, pour réduire les taux de LDL, de VLDL et de triglycérides sériques et pour augmenter les taux de HDL. L'invention concerne également des compositions pharmaceutiques et des méthodes de traitement.

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