Nicotinamide-based kinase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 213/80 (2006.01) A61K 31/44 (2006.01) A61P 5/48 (2006.01) A61P 11/06 (2006.01) A61P 17/04 (2006.01) A61P 17/06 (2006.01) A61P 29/00 (2006.01) A61P 31/14 (2006.01) A61P 31/18 (2006.01) A61P 31/20 (2006.01) A61P 35/02 (2006.01) A61P 35/04 (2006.01) C07D 213/82 (2006.01) C07D 405/04 (2006.01) C07D 405/12 (2006.01) C07D 409/04 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2508171

A compound of the general formula (I) or pharmaceutically acceptable prodrugs, salts, hydrates, solvates, crystal forms or diastereomers thereof is described. A method of treating tyrosine kinase-associated disease states in a subject using a compound of formula (I) is also described.

L'invention concerne un composé de formule générale (I) ou des promédicaments, sels, hydrates, solvates, formes cristallines ou diastéréoisomères acceptables sur le plan pharmaceutique de celui-ci. L'invention concerne également un procédé de traitement d'états pathologiques associés à la tyrosine kinase chez un sujet au moyen dudit composé.

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