Nicotinamide derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 213/81 (2006.01) A61B 8/13 (2006.01) A61K 51/04 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01) C07D 213/82 (2006.01) C07D 215/48 (2006.01) C07D 215/50 (2006.01) C07D 215/54 (2006.01) C07D 401/06 (2006.01)

Patent

CA 2753532

A compound comprising a pyridine carboxamide structure, for use in imaging or treating melanoma, is described. An aromatic ring in the structure is substituted with a radiohalogen atom and the substitution on the amide nitrogen atom is such that the compound binds to melanin.

L'invention porte sur un composé comportant une structure de pyridine-carboxamide, qui est destiné à être utilisé dans l'imagerie ou le traitement d'un mélanome. Un noyau aromatique dans la structure est substitué par un atome de radiohalogène et la substitution sur l'atome d'azote d'amide est telle que le composé se lie à la mélanine.

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