Nicotine dissolving film with or without menthol

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/70 (2006.01) A61P 25/34 (2006.01) A61K 31/465 (2006.01)

Patent

CA 2757446

A fast-dissolving film to be placed in the oral cavity of a person includes nicotine, or nicotine analog, with or without menthol, or menthol analog, that can be absorbed through the oral mucosa directly into the person's bloodstream for the purpose of reducing a temporary craving for nicotine during periods when smoking is not possible, or for therapeutic purposes, the film being thin and made from a low-moisture, non-tacky material that becomes dissolved when hydrated and that is sized so that the substrate can be placed in oral cavities of persons. From 0.1 mg to 10 mg nicotine, or a nicotine analog, and, optionally, menthol, or a menthol analog, are added to the substrate, which is then packaged in a flat, sealed container that can be unobtrusively placed into a pocket earned by the smoker, thereby making the container readily accessible to the smoker.

L'invention porte sur film à dissolution rapide destiné à être placé dans la cavité buccale d'une personne, comprenant de la nicotine, ou un analogue de nicotine, avec ou sans menthol ou analogue du menthol, pouvant être absorbé directement à travers la muqueuse buccale jusqu'à la circulation sanguine de la personne afin de réduire un état de besoin temporaire de nicotine pendant des périodes pendant lesquelles il est impossible de fumer ou pour des objectifs thérapeutiques, le film étant mince et constitué d'un matériau à faible humidité, non collant, se dissolvant lorsqu'il est hydraté et dimensionné de telle sorte que le substrat peut être placé dans des cavités buccales de personnes. On ajoute au substrat de 0,1 mg à 10 mg de nicotine ou d'analogues de la nicotine, et facultativement du menthol ou un analogue du menthol, le substrat étant ensuite conditionné dans un boîtier scellé plat qui peut être placé de façon non indiscrète dans une poche du fumeur, rendant ainsi le boîtier facilement accessible au fumeur.

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