Nicotinic acetylcholine receptor ligands

Details Nicotinic acetylcholine receptor ligands Nicotinic acetylcholine receptor ligands

C - Chemistry, Metallurgy

07

D

C07D 453/02 (2006.01) A61K 31/439 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2550844

Compounds of formula (I), wherein D, Ar1, E and Ar2 are as defined in the specification, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, especially in the treatment or prophylaxis of psychotic and intellectual impairment disorders.

La présente invention concerne des composés représentés par la formule générale (I) dans laquelle D, Ar?1¿, E et Ar?2¿ sont tels que définis dans la spécification. L'invention concerne également des procédés pour leur élaboration, des compositions pharmaceutique les contenant, et leur utilisation thérapeutique, notamment en traitement ou prophylaxie de troubles psychotiques ou de détérioration mentale.

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