Nicotinic acid esters and pharmaceutical compositions...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 213/80 (2006.01) A61K 31/44 (2006.01) C07C 69/007 (2006.01) C07C 69/587 (2006.01) C07C 69/76 (2006.01) C07D 209/28 (2006.01) C07D 213/30 (2006.01) C07D 213/55 (2006.01) C07D 213/66 (2006.01) C07D 233/94 (2006.01) C07D 279/36 (2006.01) C07D 321/00 (2006.01) C07D 339/04 (2006.01) C07D 499/00 (2006.01) C07F 9/09 (2006.01) C07F 9/655 (2006.01) C07J 1/00 (2006.01) C07J 5/00 (2006.01)

Patent

CA 2220091

Niacin as a compound, per se or for use in therapy, of structure (I), where B is -C(-O)- (nicotinic acid) or -CH2-O- (niacin alcohol), the "link" C which is optional is a diol or hydroxy carboxylic acid or dicarboxylic acid residue, and D is a fatty acid or fatty acid alcohol residue, the links between B and C and C and D being ester links.

Cette invention porte sur la niacine comme un composé en soi ou pour son usage dans des applications thérapeutiques, ledit composé ayant la structure représentée par la formule (I) dans laquelle B est -C(=O)- (acide nicotinique) ou -CH¿2?-O- (alcool de niacine), le "lien" C, par ailleurs optionnel, étant un diol ou un acide hydroxycarboxylique ou un résidu d'acide dicarboxylique, et D est un acide gras ou un résidu d'alcool d'acide gras, les liens entre B et C et entre C et D étant des liens esters.

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