Nicotinic activity of a series of arecolones and isoarecolones

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 211/70 (2006.01) A61K 31/44 (2006.01)

Patent

CA 2080536

Abstract Series of 1,2,5,6-tetrahydro-3-pyridyl ketones and 1,2,3,6-tetrahydro-4-pyridyl ketones and the physiologically acceptable acid addition salts thereof have nicotinic agonist or antagonist activity and are useful in the treatment of Alzheimer's disease,Parkinson's disease and other central nervous system disorders, pain, gastrointestinal disorders, diabetes.

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