Nitraminodiaryl sulfoxide derivatives, process for their...

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A61K 31/135 (2006.01) A01N 41/10 (2006.01)

Patent

CA 1261353

A b s t r a c t The invention relates to a new process for the preparation of nitraminodiaryl sulfoxide derivatives of the formula (I), Image (I) wherein R and R1 represent hydrogen or alkyl having from 1 to 6 carbon atoms, and R2 is hydrogen, halogen, alkyl having from 1 to 6 carbon atoms, alkoxy having from 1 to 6 carbon atoms, or phenyl or phenylthio both optionally substituted by one or more identical or different halogen(s) and/or nitro group(s), The compounds of formula (I) are pharmaceutically active, and are particularly useful in the veterinary therapy as anthelmintics. In addition they show pesticidal, particularly acaricidal, fungicidal and herbicidal properties. The invention relates also to pharmaceutical and pesticidal compositions containing as active ingredient compounds of formula (I). The compounds of formula (I), in which the substituents are as defined, with the proviso that if R2 is hydrogen - 2 - and the substituent -N(R,R1) is in para-position related to the sulfoxide group, R and R1 are other than hydrogen or methyl, are new.

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