Nitrilases, nucleic acids encoding them and methods for...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/55 (2006.01) G06F 19/22 (2011.01) C07H 21/00 (2006.01) C07K 16/40 (2006.01) C12N 9/78 (2006.01) C12N 13/00 (2006.01) C12P 7/40 (2006.01) C12P 7/42 (2006.01) C12P 19/34 (2006.01) C12P 41/00 (2006.01) C12Q 1/34 (2006.01) C12Q 1/68 (2006.01) C40B 30/02 (2006.01) G01N 31/10 (2006.01)

Patent

CA 2679503

The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.

L'invention concerne des nitrilases et des acides nucléiques codant les nitrilases. En outre, des procédés de conception de nouvelles nitrilases et un procédé d'utilisation de celles-ci sont également proposés. Les nitrilases ont une activité et une stabilité accrue à un pH et à une température accrus.

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