C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 335/32 (2006.01) A61K 31/275 (2006.01) A61K 31/277 (2006.01) A61P 35/00 (2006.01) C07D 213/04 (2006.01) C07D 215/02 (2006.01) C07D 217/02 (2006.01) C07D 417/04 (2006.01)
Patent
CA 2762427
Disclosed are nitrile derivatives and pharmaceutical compositions comprising nitrile derivatives. The pharmaceutical compositions comprise compounds of the formula I : (I) and the pharmaceutically acceptable salts of such compounds. Also disclosed are processes for the preparation of such compounds, intermediates used in the preparation of such compounds, and the uses of such compounds in treating hyperproliferative diseases, inflammatory diseases and viral and bacterial infections and inducing apoptosis in cancer cells.
Cette invention concerne des dérivés de nitrile et des compositions pharmaceutiques comprenant des dérivés de nitrile. Les compositions pharmaceutiques comprennent des composés de formule I (I) et leurs sels pharmaceutiquement acceptables. L'invention concerne également des procédés de préparation de ces composés, des intermédiaires utilisés dans la préparation de ces composés, et les utilisations de ces composés dans le traitement des maladies hyperprolifératives, des maladies inflammatoires, des infections virales et bactériennes, et dans l'induction de l'apoptose des cellules cancéreuses.
Cellceutix Corporation
Dimock Stratton Llp
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