Nitro anthracyclines, process for their preparation and use...

C - Chemistry – Metallurgy – 07 – H

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C07H 15/252 (2006.01) A61K 31/70 (2006.01)

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CA 1296325

ABSTRACT NITRO ANTHRACYCLINES, PROCESS FOR THEIR PREPARATION AND USE THEREOF Anthracycline glycosides of the general formula (A'): Image wherein R1 represents a hydrogen atom, a hydroxy group or a methoxy group; one of R2 and R3 represents a hydroxy group and the other of R2 and R3 represents a nitro gror? and R4 represents a hydrogen atom or a hydroxy group;and their pharmaceutically acceptable salts; have anti-tumor activity.

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