Nitro compounds having vasodilator activity

Details Nitro compounds having vasodilator activity Nitro compounds having vasodilator activity

C - Chemistry, Metallurgy

07

D

C07D 213/78 (2006.01) A61K 31/27 (2006.01) A61K 31/395 (2006.01) C07C 251/40 (2006.01) C07C 271/12 (2006.01) C07C 271/20 (2006.01) C07C 275/20 (2006.01) C07C 307/06 (2006.01) C07C 311/05 (2006.01) C07D 209/34 (2006.01) C07D 209/48 (2006.01) C07D 213/56 (2006.01) C07D 213/71 (2006.01) C07D 213/80 (2006.01) C07D 213/81 (2006.01) C07D 213/82 (2006.01) C07D 215/54 (2006.01) C07D 231/14 (2006.01) C07D 233/84 (2006.01) C07D 233/92 (2006.01) C07D 239/28 (2006.01) C07D 239/38 (2006.01) C07D 241/24 (2006.01) C07D 24

Patent

CA 2123569

2123569 9310097 PCTABS00022 A few nitro compound of formula (I), wherein R1 and R2 are each lower alkyl or lower alkoxy(lower)-alkyl, or (a) is cyclized to form (b), X is -O-, -S- or -NH-, m is an integer 0 or 1, and R3 is carbamoyl, lower alkylcarbamoyl, lower alkanoyl, di-lower alkylaminosulfonyl, lower alkylsulfonyl, oxamoyl or a group of the formula: -(Y)n-R4, wherein Y is -CO-, -SO2-, -COCH2 or (c), n is an integer of 0 or 1, and R4 is heterocyclic group which is optionally substituted with one or more substituents selected from lower alkyl, lower alkoxy, phenyl, carbamoyl, halogen, amino, lower alkylthio, hydroxy, lower alkylsulfonylamino and carbamoylmethyl, and pharmaceutically acceptable salt thereof, which are useful for vasodilator.

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