Nitrogen- and sulfur-containing lipid compounds, their...

Details Nitrogen- and sulfur-containing lipid compounds, their... Nitrogen- and sulfur-containing lipid compounds, their...

C - Chemistry, Metallurgy

07

C

167/179, 260/470

C07C 317/04 (2006.01) A61K 31/14 (2006.01) C07D 213/02 (2006.01) C07D 213/20 (2006.01) C07D 277/22 (2006.01)

Patent

CA 1298297

Abstract of the Disclosure A compound of the general formula [I]: Image [I] wherein R1 represents a higher alkyl group or an N-(higher alkyl)carbamoyl group, R2 represents hydrogen, a lower alkyl group, an acyl group having at least three carbon atoms, an N-(lower alkyl)carbamoyl group, an N-(lower alkyl)thiocar- bamoyl group or a benzyl group, R represents a primary, secondary or tertiary amino group or a quaternary ammonium group, x is 1 or 2, y is a number of 0, 1 or 2, and z is an integer of 2-10, or a pharmaceutically acceptable salt thereof. The novel substances have both anti-tumor activity and platelet activating factor-inhibiting property, and they are effective as an anti-tumor agent without circulatory trouble.

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