C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/242.01
C07D 471/04 (2006.01)
Patent
CA 1130284
ABSTRACT This invention relates to new nitrogen bridgehead condensed pyrimidine derivatives and process for their preparation. These new compounds can be used in therapy first of all as anti-allergic and anti- asthmatic agents. Our invention also relates to pharmaceutical compositions containing these compounds. It is known that pyrido(1,2-a)pyrimidine derivatives possess valuable analgetic and other central nerval system influencing properties (British Patent No. 1,209,946). One of the most preferred representatives of these compounds used in clinical practice as analgetic is the 1,6-dimethyl-3-ethoxy- carbonyl-4-oxo-4H-pyrido(1,2-a)-pyrimidinium-metho- sulfate. (PROBONR, Rimazolium) {Arzneimittelforschung 22, 815 /1972/]. Pyrido(1,2-a)pyrimidine derivatives may be prepared by cyclisation of the corresponding dialkyl-(2-pyridyl-amino-methylene)-malonate. Other substituted pyrido(1,2-a)pyrimidine derivatives are described in British Patent No. 1,454,312.
318811
Bitter Istvan
Breining Tibor
Hermecz Istvan
Horvath Agnes
Mandi Attila
Chinoin Gyogyszer - Es Vegyeszeti Termekek Gyara Rt.
Fetherstonhaugh & Co.
LandOfFree
Nitrogen bridgehead compounds having anti-allergic effect... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Nitrogen bridgehead compounds having anti-allergic effect..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nitrogen bridgehead compounds having anti-allergic effect... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-608486