Nitrogen compounds

Details Nitrogen compounds Nitrogen compounds

C - Chemistry, Metallurgy

07

D

167/226, 260/277

C07D 401/12 (2006.01) A61K 31/47 (2006.01) C07D 215/22 (2006.01) C07D 405/14 (2006.01) C07D 491/056 (2006.01)

Patent

CA 2023229

PH 35394 ABSTRACT NITROGEN COMPOUNDS The invention concerns pharmaceutically useful novel compounds of the formula I, Image I in which R1, R2, R3, R4, R5, Ra, A, X and Z have the various meanings defined herein, and their non-toxic salts, and pharmaceutical compositions containing them. The novel compounds are of value in treating conditions such as hypertension and congestive heart failure. The invention further concerns processes for the manufacture of the novel compounds and the use of the compounds in medical treatment.

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