C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/94 (2006.01) A61K 31/517 (2006.01) A61P 35/00 (2006.01) C07D 239/95 (2006.01)
Patent
CA 2592900
Disclosed are 4-arylamino-quinazolines and analogs thereof effective as activators of caspases and inducers of apoptosis. The compounds of this invention are useful in the treatment of a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.
L'invention concerne des 4-arylamino-quinazolines et des analogues de celles-ci, efficaces en tant qu'activateurs de caspases et inducteurs d'apoptose. Les composés selon l'invention sont utiles dans le traitement de divers états cliniques caractérisés par une croissance et une propagation incontrôlées de cellules anormales.
Anderson Mark B.
Cai Sui Xiong
Sirisoma Nilantha Sudath
Suzuki Kazuyuki
Willardsen Adam
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Cytovia Inc.
Myriad Genetics Inc.
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