Nitrogen containing heteroaromatics as factor xa inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 207/34 (2006.01) A61K 31/40 (2006.01) A61K 31/41 (2006.01) C07D 231/14 (2006.01) C07D 231/16 (2006.01) C07D 231/18 (2006.01) C07D 231/40 (2006.01) C07D 231/42 (2006.01) C07D 233/90 (2006.01) C07D 249/06 (2006.01) C07D 249/10 (2006.01) C07D 257/04 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2275796

The present application describes nitrogen containing heteroaromatics and derivatives thereof of formula (I) or pharmaceutically acceptable salt or prodrug forms thereof, wherein J is N or NH and D may be C(=NH)NH2, which are useful as inhibitors of factor Xa.

La présente invention se rapporte à des composés hétéroaromatiques contenant de l'azote et à des dérivés de tels composés représentés par la formule (I), ou à des sels ou bioprécurseurs pharmaceutiquement acceptables de ces composés utiles en tant qu'inhibiteurs du facteur Xa. Dans la formule (I), J est N ou NH et D peut être C(=NH)NH¿2?.

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