C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 241/24 (2006.01) A61K 31/4965 (2006.01) A61K 31/50 (2006.01) A61K 31/513 (2006.01) A61K 31/53 (2006.01) A61P 31/12 (2006.01) A61P 31/16 (2006.01) C07D 237/24 (2006.01) C07D 239/36 (2006.01) C07D 253/07 (2006.01) C07D 253/075 (2006.01)
Patent
CA 2339272
Nitrogenous heterocyclic carboxamide derivatives represented by general formula (I), or salts thereof are useful as preventives and therapeutic agents for infections with viruses, particularly influenza virus. In said formula A is an optionally substituted pyrazine, pyrimidine, pyridazine or triazine ring; R1 is O or OH; R2 is hydrogen, acyl, or optionally substituted carbamoylalkyl or carboxyalkyl; and the broken line represents a single or double bond.
La présente invention concerne des dérivés hétérocycliques azotés de carboxamide représentés par la formule générale (I) ou certains de leurs sels, lesquels dérivés et sels conviennent comme agents préventifs et thérapeutiques pour les infections à virus, et notamment le virus de la grippe. En l'occurrence, A est un cycle pyrazine, pyrimidine, pyridazine ou triazine éventuellement modifié. R<1> est O ou OH; R<2> est hydrogène, acyle, carbamoylalkyle ou carboxyalkyle éventuellement substitué. La ligne tiretée représente une liaison simple ou double.
Egawa Hiroyuki
Furuta Yousuke
Marks & Clerk
Toyama Chemical Co. Ltd.
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