Nitrogen heterocycle biaryls for osteoporosis and other...

C - Chemistry – Metallurgy – 07 – D

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C07D 235/30 (2006.01) A61K 31/4184 (2006.01) A61P 35/00 (2006.01) C07D 215/38 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01)

Patent

CA 2611971

Nitrogen heterocycle biaryls having a carboxylate terminus are useful for treating endometriosis, osteoporosis, restenosis following angioplasty, rheumatoid arthritis, cancer, macular degeneration and obesity. Compounds of formula: (I) are disclosed. A representative example is : (II)

La présente invention concerne des biaryles à hétérocycle azote qui possèdent une extrémité carboxylate et qui sont utiles pour le traitement de l'endométriose, de l'ostéoporose, de la resténose après angioplastie, de la polyarthrite rhumatoïde, du cancer, de la dégénérescence maculaire et de l'obésité. Des composés de formule : (I) sont présentés. Un exemple représentatif est : (II)

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