Nitrogenated derivatives of pancratistatin

Details Nitrogenated derivatives of pancratistatin Nitrogenated derivatives of pancratistatin

C - Chemistry, Metallurgy

07

D

C07D 491/04 (2006.01) A61K 31/4525 (2006.01) A61K 31/473 (2006.01)

Patent

CA 2731901

The present invention concerns nitrogenated derivatives of narciclasine and pancratistatin of the following general formula (I) as well as their pharmaceutically acceptable salts. The present invention also concerns the use of these compounds in cancer therapy as well as a method for their preparation.

La présente invention concerne des dérivés azotés de narciclasine et de pancratistatine représentés par la formule générale suivante (I) ainsi que leurs sels pharmaceutiquement acceptables. La présente invention concerne également l'utilisation de ces composés pour le traitement du cancer ainsi qu'un procédé permettant de les préparer.

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