C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/10 (2006.01) A61K 31/4523 (2006.01) A61K 31/4545 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2464721
The invention concerns a compound of formula (I), (see formula I) wherein: X represent N or CH; R1 represents a hydrogen or halogen atom or a CF3 group; R2 and R3 independently represent a hydrogen atom or a C1-C4 alkyl group; R4 represents a hydrogen atom or a C1-C4 alkyl group; n is 0 or 1; A represents a heterocycle selected among pyridine, pyrimidine, pyrazine and pyridazine optionally mono-or di-substituted by a C1-C4 alkyl or C1-C4 alkoxy group; and their N-oxides and their salts or solvates.
Composé de formule (I) : dans laquelle X représente N ou CH; R¿1? représente un atome d'hydrogène ou d'halogène ou un groupe CF¿3?; R¿2? et R¿3? représentent indépendamment un atome d'hydrogène ou un groupe (C¿1?-C¿4?) alkyle; R¿4? représente un atome d'hydrogène ou un groupe (C¿1?-C¿4?) alkyle; n est 0 ou 1; A représente un hétérocycle choisi parmi la pyridine, la pyrimidine, la pyrazine et la pyridazine éventuellement mono- ou di-substituées par un groupe (C¿1?-C¿4?) alkyle ou (C¿1?-C¿4?) alcoxy; ainsi que leurs N-oxydes et leurs sels ou solvates.
Baroni Marco
Bourrie Bernard
Pierre Casellas
Puleo Letizia
Kirby Eades Gale Baker
Sanofi-Aventis
Sanofi-Synthelabo
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