Nitroimidazoles

C - Chemistry – Metallurgy – 07 – D

Patent

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260/280, 260/301

C07D 417/06 (2006.01)

Patent

CA 1078390

ABSTRACT OF THE DISCLOSURE: The invention is concerned with novel nitroimidazolyl- vinylthiadiazoles having the general formula: Image (I) where R1 is alkyl of 1 to 4 carbon atoms, R2 is hydrogen or methyl, and R3 is hydrogen, alkyl of 1 to 6 carbon atoms, phenyl or pyridyl. These compounds are useful as chemotherapeutics in the treatment of microbial infections in humans and animals, especially of trichomoniasis, trypano- somiasis and amoebic dysentery.

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