C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/50 (2006.01) A61K 31/41 (2006.01) A61K 31/495 (2006.01) A61P 9/00 (2006.01) A61P 29/00 (2006.01) C07D 239/76 (2006.01)
Patent
CA 2641501
The present invention relates to alpha2-adrenergic receptor agonist nitrooxyderivatives of formula (I), wherein A is selected from (Ia) or (Ib) having improved pharmacological activity and enhanced tolerability. They can be employed for the treatment of ocular diseases, in particular high intraocular pressure and glaucoma. A-X1-Y-ONO2 (I)
La présente invention concerne des dérivés nitrooxy agonistes des récepteurs alpha 2-adrénergiques de formule (I), dans laquelle A est choisi parmi (Ia) ou (Ib), ayant une activité pharmacologique améliorée et une plus grande tolérabilité. Ils peuvent être employés pour le traitement de maladies oculaires, en particulier l'hypertension intraoculaire et le glaucome. A-X1-Y-ONO2 (I)
Benedini Francesca
Biondi Stefano
Chong Wesley Kwan Mung
Impagnatiello Francesco
Ongini Ennio
Gowling Lafleur Henderson Llp
Nicox S.a.
Pfizer Inc.
LandOfFree
Nitrooxy-comprising derivatives of apraclonidine and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Nitrooxy-comprising derivatives of apraclonidine and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nitrooxy-comprising derivatives of apraclonidine and... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1844502