Nitroquinolone derivatives as nmda antagonists

Details Nitroquinolone derivatives as nmda antagonists Nitroquinolone derivatives as nmda antagonists

C - Chemistry, Metallurgy

07

D

C07D 215/16 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07D 215/22 (2006.01) C07D 401/00 (2006.01) C07D 405/00 (2006.01) C07D 409/00 (2006.01) C07D 413/02 (2006.01) C07D 413/06 (2006.01) C07D 417/02 (2006.01)

Patent

CA 2126076

2126076 9314067 PCTABS00024 A class of optionally 4-substituted 3-nitro-2-oxo-1,2,3,4-tetrathydroquinoline derivatives are selective non-competitive antagonists of NMDA receptors and/or are antagonists of AMPA receptors, and are therefore of utility in the treatment of conditions, such as neurodegenerative disorders, convulsions or schizophrenia, which require the administration of an NMDA and/or AMPA receptor antagonist.

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