Nitrosodiphenylamine derivatives and their pharmaceutical...

C - Chemistry – Metallurgy – 07 – D

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C07D 213/75 (2006.01) A61K 31/13 (2006.01) A61K 31/15 (2006.01) A61K 31/44 (2006.01) A61P 39/06 (2006.01) C07C 237/40 (2006.01) C07C 243/06 (2006.01) C07D 207/09 (2006.01) C07D 213/40 (2006.01) C07D 213/76 (2006.01) C07D 233/54 (2006.01) C07D 239/42 (2006.01) C07D 295/12 (2006.01) C07D 295/13 (2006.01) C07D 295/135 (2006.01) C07D 453/02 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2478652

Compounds of formula (I) in which each of the phenyl rings represented is optionally substituted one or more times; n represents an integer selected from 0, 1, 2, 3, 4 and 5; W represents -CO-or -SO2-; Z represents H; alkyl; aryl; or arylalkyl; R1 represents any monovalent organic group; and the pharmaceutically acceptable salts thereof, can be used in the treatment of pathologies that are characterized by an oxidative stress condition.

L'invention concerne les composés de la formule (I) dans laquelle chaque noyau phényle représenté est éventuellement substituté au moins une fois; n représente un nombre entier sélectionné parmi 0, 1, 2, 3, 4 et 5; W représente -CO-ou -SO¿2?-; Z représente H, alkyle, aryle ou arylalkyle; R¿1? représente un groupe organique monovalent quelconque. Ces composés et leurs sels pharmaceutiquement acceptables peuvent être utilisés pour traiter les pathologies caractérisées par un état de stress oxydatif.

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