Nitrosourea derivatives

Details Nitrosourea derivatives Nitrosourea derivatives

C - Chemistry, Metallurgy

07

H

260/229

C07H 5/04 (2006.01) C07H 13/12 (2006.01)

Patent

CA 1081216

NOVEL NITROSOUREA DERIVATIVES ABSTRACT OF THE DISCLOSURE Novel nitrosourea derivatives are provided which possess a high inhibitory activity against the leukemia and tumors with a low toxicity and a good stability against humidity and which are useful for pharmaceutical purposes. The compounds have the structure: Image wherein R1 represents hydroxyl or alkanoyloxy containing 2-4 carbon atoms; R2 represents hydrogen or alkanoyl containing 2-4 carbon atoms; R3 repre- sents alkanoyl containing 2-4 carbon atoms; and R4 represents alkyl or halo-substituted alkyl containing 1-4 carbon atoms. - 1 -

285901

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