Nitroxy steroids

C - Chemistry – Metallurgy – 07 – J

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C07J 41/00 (2006.01) A61K 31/573 (2006.01) A61K 31/575 (2006.01)

Patent

CA 2586538

Steroidal compounds or their salts having general formulas (I) and (II) wherein: s is an integer equal to 1 or 2, preferably s - 2: b0 = 0 or 1; A = R-, wherein R is the steroidal drug radical, C and C1 are two bivalent radicals. The precursors of the radicals B and B1 are such as to meet the pharmacological tests reported in the description.

L'invention porte sur des composés stéroïdiens ou leurs sels présentant les formules générales (I) et (II) où s est un nombre entier égal à 1 ou 2, de préférence s = 2; b0 = 0 ou 1; A = R-, où R est le radical du médicament stéroïdien, C et C1 constituent deux radicaux bivalents. Les précurseurs des radicaux B et B1 sont tels qu'ils satisfont aux tests pharmacologiques mentionnés dans la description.

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