Nitroxyalkylamide derivative

Details Nitroxyalkylamide derivative Nitroxyalkylamide derivative

C - Chemistry, Metallurgy

07

D

C07D 261/12 (2006.01) A61K 31/21 (2006.01) A61K 31/33 (2006.01) C07C 235/20 (2006.01) C07C 271/48 (2006.01) C07C 271/52 (2006.01) C07C 323/41 (2006.01) C07C 323/60 (2006.01) C07D 261/08 (2006.01) C07D 261/10 (2006.01) C07D 263/36 (2006.01) C07D 275/03 (2006.01) C07D 277/34 (2006.01) C07D 307/68 (2006.01) C07D 307/71 (2006.01) C07D 319/20 (2006.01) C07D 333/38 (2006.01)

Patent

CA 2123101

Nitroxyalkylamide derivatives having the general formula: R1 - (A)n-CONH-B-ONO2 (I) wherein: R1 represents an optionally substituted heterocyclic, heterocyclic-oxy, aryloxy or arylthio group; A represents a C1-C4 alkylene group; B represents a C1-C4 alkylene group; and n is 0 or 1. The compounds of the present invention have an excellent vasodilator action for collateral vessels and an anti- anginal action, and are useful as therapeutic agents for angina pectoris.

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