Nk-1 receptor antagonists for prevention of neurogenic...

Details Nk-1 receptor antagonists for prevention of neurogenic... Nk-1 receptor antagonists for prevention of neurogenic...

A - Human Necessities

61

K

A61K 31/445 (2006.01) A61K 31/40 (2006.01) A61K 31/435 (2006.01) A61K 31/439 (2006.01) A61K 31/451 (2006.01) A61K 31/454 (2006.01) A61K 31/47 (2006.01) A61K 31/4709 (2006.01)

Patent

CA 2228572

The present invention relates to a method of preventing or treating the neurogenic inflammation associated with the use of viral vectors in gene therapy in a mammal, including a human, by administering to the mammal an NK-1 receptor antagonist (e.g., a substance P receptor antagonist).

L'invention concerne un procédé de prévention ou de traitement de l'inflammation neurogène associée à l'utilisation de vecteurs viraux en thérapie génique chez un mammifère, y compris l'homme, par administration audit mammifère d'un antagoniste du récepteur NK1 (par exemple, un antagoniste du récepteur de la substance P).

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