A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/445 (2006.01) A61K 31/135 (2006.01) A61K 31/137 (2006.01) A61K 31/40 (2006.01) A61K 31/435 (2006.01) A61K 31/438 (2006.01) A61K 31/451 (2006.01) A61K 31/4535 (2006.01) A61K 31/454 (2006.01) A61K 31/55 (2006.01) A61K 31/675 (2006.01)
Patent
CA 2205016
The present invention relates to a method of treating or preventing a disorder of the eye selected from glaucoma, ocular hypertension, miosis, excess lacrimation, hyperemia and breakdown of the blood aqueous barrier in mammals, including humans, using an NK-1 antagonist. It also relates to a method of treating or preventing such disorders in mammals, including humans, using certain quinuclidine derivatives, piperidine derivatives, pyrrolidine derivatives, azanorbornane derivatives, ethylene diamine derivatives and related compounds that are substance P receptor antagonists.
La présente invention concerne un procédé de traitement ou de prévention d'un trouble oculaire dont le glaucome, l'hypertonie oculaire, la myosis, le larmoiement excessif, l'hyperémie, et la rupture de la barrière aqueuse du sang chez les mammifères, y compris chez l'homme, à l'aide d'un antagoniste du NK-1. L'invention concerne également un procédé de traitement ou de prévention de tels troubles chez les mammifères, y compris l'homme, à l'aide de certains dérivés de quinuclidine, de dérivés de pipéridine, de dérivés de pyrrolidine, de dérivés d'azanorbornane, de dérivés d'éthylène diamine et des composés correspondants qui sont des antagonistes du récepteur de la substance P.
Pfizer Inc.
Smart & Biggar
LandOfFree
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