Nk3 receptor in vivo assay

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/00 (2006.01) A61K 38/08 (2006.01) A61P 25/18 (2006.01)

Patent

CA 2557246

The present invention relates to a method of assessing the in vivo potency of a NK3 receptor antagonist comprising: a) the non-human animal with the NK3 receptor antagonist of interest, b) treating an non-human animal with a NK3 R agonist treating, c) measuring the activity of the treated non-human animal, and d) correlating the effect of the antagonist of interest on the activity of the treated non-human animal with the in vivo potency of the antagonist.

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