C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/20 (2006.01) A61K 31/197 (2006.01) A61K 31/405 (2006.01) A61K 31/63 (2006.01) C07C 229/42 (2006.01)
Patent
CA 2061836
The present invention is directed to a class of 4,6- disubstituted tryptophan derivatives, 4,6-disubstituted kynurenines, their use as NMDA antagonists and to pharmaceutical compositions containing these compounds. In a specific embodiment of this invention compounds of formulae (Ia) and (Ib) are disclosed and claimed. (see formulae Ia and Ib) Wherein X and Y are as described herein.
Mcdonald Ian A.
Palfreyman Michael G.
Salituro Francesco G.
Schwarcz Robert
Aventisub II Inc.
Merrell Dow Pharmaceuticals Inc.
Osler Hoskin & Harcourt Llp
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